Case Report of a Patient with Recrudescent Malaria in Rural Kenya
DOI:
https://doi.org/10.47672/ejhs.1526Keywords:
Smear-Positive Malaria, Recrudescence, Artemisinin, PrimaquineAbstract
A patient in rural Kenya presented with recurrent smear-positive non-severe malaria, despite multiple re-treatments with both oral and parenteral artemisinin-base combination therapies. Recrudescence of P. falciparum malaria was deemed the most likely explanation, and radical treatment with Primaquine was finally done, with subsequent remission of malaria symptoms and negative follow-up laboratory tests.
Downloads
References
White, M.T., et al., Plasmodium vivax and Plasmodium falciparum infection dynamics: re-infections, recrudescences and relapses. Malar J, 2018. 17(1): p. 170.
White, N.J., The assessment of antimalarial drug efficacy. Trends Parasitol, 2002. 18(10): p. 458-64.
Epidemiology of malaria in Kenya. Afr J Med Pract, 1994. 1(1): p. 5-6.
Vinetz, J.M., et al., Plasmodium malariae infection in an asymptomatic 74-year-old Greek woman with splenomegaly. N Engl J Med, 1998. 338(6): p. 367-71.
Ashley, E.A., J. Recht, and N.J. White, Primaquine: the risks and the benefits. Malar J, 2014. 13: p. 418.
Mavoko, H.M., et al., Efficacy and safety of re-treatment with the same artemisinin-based combination treatment (ACT) compared with an alternative ACT and quinine plus clindamycin after failure of first-line recommended ACT (QUINACT): a bicentre, open-label, phase 3, randomised controlled trial. Lancet Glob Health, 2017. 5(1): p. e60-e68.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Vonwicks Czelestakov Onyango
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.