Pulmonary Embolism and Wilms’ Tumor. Can It Be Any Worse? Case Report

Authors

  • Abdulrahaman Al Zhrani
  • Abdullah Baothman

DOI:

https://doi.org/10.47672/ajhmn.694
Abstract views: 165
PDF downloads: 188

Keywords:

Nephroblastoma, pulmonary embolism, Wilms' tumor.

Abstract

It is common for Wilms tumor to invade the inferior vena cava and right atrium, but a massive pulmonary embolism is rare. This case report describes an 8-year-old male patient who presented to an outpatient clinic with mild pain associated with subjective fever for 1 week. A left renal mass with extension of an inferior vena cava thrombus was seen on abdominal computed tomography, suggesting a Wilms tumor. An exploratory laparotomy biopsy was scheduled, but not completed because the patient’s health suddenly deteriorated, and he died despite high-quality cardiopulmonary resuscitation. A massive pulmonary embolism was found to cause a sudden and fatal cardiac arrest.

 

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Author Biographies

Abdulrahaman Al Zhrani

King Saud bin Abdul-Aziz University for Health Sciences, Jeddah, Saudi Arabia.

Abdullah Baothman

King Saud bin Abdul-Aziz University for Health Sciences, Jeddah, Saudi Arabia.

Princess Norah Oncology Center, King Abdul-Aziz Medical City-Jeddah, Saudi Arabia

References

Ceelen, W., Kerremans, I., Lutz-Dettinger, N., Vandenbroeck, P., & Hemptinne, B. (1997). Wilms’ Tumour Presenting as a Pulmonary Embolism. Acta Chirurgica Belgica, 97, 148–150.

Davidoff, A. M. (2009). WILMS TUMOR. Current Opinion in Pediatrics, 21(3), 357–364. https://doi.org/10.1097/MOP.0b013e32832b323a

Dome, J. S., Rodriguez-Galindo, C., Spunt, S. L., & Santana, V. M. (2020). 92—Pediatric Solid Tumors. In J. E. Niederhuber, J. O. Armitage, M. B. Kastan, J. H. Doroshow, & J. E. Tepper (Eds.), Abeloff’s Clinical Oncology (Sixth Edition) (pp. 1703-1747.e11). Elsevier. https://doi.org/10.1016/B978-0-323-47674-4.00092-X

Fukuda, A., Isoda, T., Sakamoto, N., Nakajima, K., & Ohta, T. (2019). Lessons from a patient with cardiac arrest due to massive pulmonary embolism as the initial presentation of Wilms tumor: A case report and literature review. BMC Pediatrics, 19(1), 39. https://doi.org/10.1186/s12887-019-1413-y

Giannoulia-Karadana, A., Moschovi, M., Koutsovitis, P., Tolis, G., & Tzortzatou-Stathopoulou, F. (2000). Inferior vena cava and right atrial thrombosis in children with nephroblastoma: Diagnostic and therapeutic problems. Journal of Pediatric Surgery, 35(10), 1459–1461. https://doi.org/10.1053/jpsu.2000.16414

Lall, A., Pritchard-Jones, K., Walker, J., Hutton, C., Stevens, S., Azmy, A., & Carachi, R. (2006). Wilms’ tumor with intracaval thrombus in the UK Children’s Cancer Study Group UKW3 trial. Journal of Pediatric Surgery, 41(2), 382–387. https://doi.org/10.1016/j.jpedsurg.2005.11.016

Mohammadi, A. (2011). Recurrent pulmonary tumoral embolism and sudden death as the presenting symptom of Wilms’ tumor. Tuberkuloz Ve Toraks, 59(3), 271–275. https://doi.org/10.5578/tt.2405

Mushtaq, I., Carachi, R., Roy, G., & Azmy, A. (1996). Childhood renal tumours with intravascular extension. British Journal of Urology, 78(5), 772–776. https://doi.org/10.1046/j.1464-410X.1996.02020.x

National Health Information Center (last). (2019). Saudi Cancer Registry. Cancer Incidence Report, Saudia Arabia 2016. Saudi Arabia: Saudi Health Council; 2019. National Health Information Center.

Quencer, K. B., Friedman, T., Sheth, R., & Oklu, R. (2017). Tumor thrombus: Incidence, imaging, prognosis and treatment. Cardiovascular Diagnosis and Therapy, 7(Suppl 3), S165–S177. https://doi.org/10.21037/cdt.2017.09.16

Ratajczyk, K., Czekaj, A., Rogala, J., & Kowal, P. (2018). Adult Wilms tumor with inferior vena cava thrombus and distal deep vein thrombosis – a case report and literature review. World Journal of Surgical Oncology, 16(1), 38. https://doi.org/10.1186/s12957-018-1343-4

Ritchey Michael L., Kelalis Panayotis P., Breslow Norman, Offord Kenneth P., Shochat Stephen J., & D’Angio Giulio J. (1988). Intracaval and Atrial Involvement with Nephroblastoma: Review of National Wilms Tumor Study-3. Journal of Urology, 140(5 Part 2), 1113–1118. https://doi.org/10.1016/S0022-5347 (17)41975-6

Shamberger, R. C., Ritchey, M. L., Haase, G. M., Bergemann, T. L., Loechelt-Yoshioka, T., Breslow, N. E., & Green, D. M. (2001). Intravascular Extension of Wilms Tumor. Annals of Surgery, 234(1), 116–121.

Szavay, P., Luithle, T., Semler, O., Graf, N., & Fuchs, J. (2004). Surgery of cavoatrial tumor thrombus in nephroblastoma: A report of the SIOP/GPOH study. Pediatric Blood & Cancer, 43(1), 40–45. https://doi.org/10.1002/pbc.20056

Xu, S., Sun, N., Zhang, W.-P., Song, H.-C., & Huang, C.-R. (2019). Management of Wilms tumor with intravenous thrombus in children: A single center experience. World Journal of Pediatrics, 15(5), 476–482. https://doi.org/10.1007/s12519-019-00272-0

Zakowski, MF, Rh, E., & Et, M. (1990). Wilms’ tumor presenting as sudden death due to tumor embolism. Archives of Pathology & Laboratory Medicine, 114(6), 605–608.

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Published

2021-04-09

How to Cite

Al Zhran, A., & Baothman, A. . (2021). Pulmonary Embolism and Wilms’ Tumor. Can It Be Any Worse? Case Report. American Journal of Health, Medicine and Nursing Practice, 6(2), 10 - 16. https://doi.org/10.47672/ajhmn.694

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