Assessment of Serum Level of Highly Sensitive C-reactive Protein (Hs-CRP) and Uric Acid among Adult Athletes in Aba Metropolis
DOI:
https://doi.org/10.47672/ajhmn.1317Keywords:
C -reactive protein, Dyslipidemia, Hyperuricemia, Strenuous aerobic activity, exercise.Abstract
Purpose: The long-term positive effect of physical activity on the incidence of coronary artery disease, hypertension, dyslipidemia, obesity, and life expectancy are well known. This has led to many stressing the importance of exercising to promote optimal health. This study is therefore aimed at evaluating the effect of physical exercise on serum level of highly sensitive C-reactive protein (Hs-CRP) and Uric acid among adult athletes in Aba Metropolis of Abia State.
Methodology: Hundred adults were used for the study. Fifty subjects served as control and were randomly selected. The remaining fifty, twenty-five were males and twenty-five were females. Thirteen out of the twenty-five males and females exercise regularly while twelve exercises seldom. However for inclusion criteria the person had to be an athlete and for exclusion criteria, persons with cardiovascular diseases, diabetes mellitus, stroke rheumatoid arthritis and those with chronic obstructive pulmonary diseases were excluded. Blood sample was collected by venipuncture and was used to determine Highly Sensitive C-Reactive protein (Hs-CRP) and Uric Acid using Enzyme Linked Immunoassay machine and Semi automated Analyzer respectively. Data generated were analyzed using Statistical Package for Social Sciences (SPSS Version 25), One-way Analysis of Variance (ANOVA) and student t- test. Significance level for analysis was set at P-value 0.05 (P=<0.05).
Findings: The result from the study revealed that regularly exercising athletes had significantly lower Hs-CRP values than the control group. Observed as well was that regularly exercising athletes had lower HsCRP values than seldom-exercising athletes. Conversely, the uric acid level of those that exercise regularly increased compared to those seldomly exercise. This study has yet added to the need and importance of exercise in order to stay in optimal health.
Recommendation: People without health issue should be encouraged to exercise regularly but this should not be outside consulting their health care giver.
Downloads
References
Albert, M. A., Glynn, J., and Rider, P. M. (2017). Effects of Physical Activity on Serum C - reactive protein. Amplified journey of Cardiology. 23: 221-225.
Cochran, W.G (1977). Sampling techniques (3rd edition). New York: Library of congress cataloguing in publication data.
Daniel, W.W, Biostatistics: a foundation for analysis in the health sciences. (1999). 7th edition. New York: John Wiley & Sons;
Febbraio, M.A and Pederson,B.K. (2018)Muscle- derived interleukin-6:Mechanism for Activation and Possible biological Roles FASEB Journal 16: 1335-1347.
Heining, M., Johnson. J., (2016). Role of uric acid in hypertension, renal disease and metabolic syndrome. Cleveland clinic journal of Medicine. 73 (12): 1059-1064.
Mantovani, A., Garlands, X., Doni, A., And Bottazzi, B. (January 2008). "Pentraxins in innate immunity: from C - reactive protein to the long pentraxin PTX3". Journal of Clinical Immunology. 28 (1): 1-13.
Mayer-Davis E. J., D'Agostino, R. Jr., Karter, A. J. (2015). Intensity and amount of physical activity in relation to insulin sensitivity: the insulin resistance Atherosclerosis Study. The Journal of the American Medical Association. 279: 669-674.
Powers, S. K., Ji, L. L., and Leeuwenburgh, C. (2014). Executive Training-Induced Alterations in Skeletal Muscle Antioxidant Capacity. A Brief Review. Medical Science Sports Exercise Journal. 31:987-997.
Rakestraw, N. (2017). "Chemical Factors in Fatigue: The Effects of Mercury Exercise upon Certain Common Blood Constituents". Journal of Biological Chemistry 47: 565-591.
Shern, B. R, Santanam,N,W25etzstein,C,White,W.J.,and Parthasarathy,S (2017 )Exercise and Cardiovascular Disease:A New Perspective.Arteriosclerosis,Thrombosis and Vascular Biology 18:1181-1187.
Thompson,D.Pepys,M.B., and Wood,S.P. . (2009). The Physiological structure of Human C-Reactive protein and its complex with phosphocholine .Structure 7 ( 2) 169-77.
Verdaet, D., Dendale, P., De Bacquer, D., Delanghe, J., Block, P., and De Backer, G. (2017). Association between leisure time physical activity and markets of inflammation related to coronary heart disease. Artherosclerosis, 176: 303-310.
Wilson, C., Heads, A., Shenkin, A., Amanda Improve, C. W. (2014). "C-Reactive Protein, Antiproteases and Complement Factors as Objectives Markers of severity in Acute Pancreatitis". British Journal. 76:177-81
Witztum,J.L.(2017)Immunological R.5esponse to Oxidized Low Density Lipoprotein and Atherosclerosis Coronary Heart Disease. Arteriosclerosis, Thrombosis and Vascular Biology. 23: 2063-2069.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Ikpeazu V.O, Chikezie J, Chigbu L.N, Offiah S.A.U, Umeh S.U, Igboh N.M
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
